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Macrophage Nrf2 activates genes encoding CD36, heme oxygenase-1 and other stress proteins in response to oxLDLs and other byproducts of lipid peroxidation (240)

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This interference with glycolysis disrupts Th17 cell differentiation, thereby alleviating rheumatoid arthritis ( + T cells from the peripheral blood of patients with rheumatoid arthritis, catalpol upregulates miR-143-3p, inhibits the abnormal differentiation of Th17 cells, and downregulates glycolysis, thereby regulating the immune balance and exerting anti-inflammatory effects (Shen et al., 2022

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