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The flora with increased abundance includes Lactobacillus salivarius , Staphylococcus , Corynebacterium , Bacteroides fragilis , Ruminococcus gnavus , Veillonella parvula , Pseudobutyrivibrio , Escherichia/Shigella , and Streptococcus parasanguinis (201, 203, 204)

Additionally, in the renal cortex, hyperuricemia amplifies the activity of the renin-angiotensin-aldosterone (RAA) system, fostering sustained vasoconstriction of the afferent arterioles

These medications work by mimicking natural hormones that regulate blood sugar and appetite, leading to improved glycemic control and significant weight loss in many patients

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